Craig E, Schlessinger D, Gurgo C
J Bacteriol. 1972 Jul;111(1):66-72. doi: 10.1128/jb.111.1.66-72.1972.
A standard stringent strain of Escherichia coli makes little or no ribosomal ribonucleic acid (RNA) during starvation for an essential amino acid, whereas the isogenic relaxed strain makes both ribosomal and messenger RNA. A third class of strains was found which continues to make ribosomal RNA during starvation, but the RNA made is apparently unstable. There is little accumulation of RNA in the third class of strains, and few complete newly formed chains of (3)H-ribosomal RNA are observed in sedimentation analyses, even after long labeling times.
一种标准的严格型大肠杆菌菌株在必需氨基酸饥饿期间几乎不产生或不产生核糖体核糖核酸(RNA),而等基因的松弛型菌株则同时产生核糖体RNA和信使RNA。发现了第三类菌株,它们在饥饿期间继续产生核糖体RNA,但产生的RNA显然不稳定。在第三类菌株中RNA几乎没有积累,并且在沉降分析中即使经过长时间标记,也很少观察到完整的新形成的(3)H-核糖体RNA链。