Dym M, Romrell L J
J Reprod Fertil. 1975 Jan;42(1):1-7. doi: 10.1530/jrf.0.0420001.
Although lymphocytes are never present in 'normal ' seminiferous epithelium, they are found in the terminal portions of the seminiferous tubles near their junctions with the tubuli recti. Intraepithelia lymphocytes are also found in the tubuli recti testis, ductuli efferentes, epididymis and ductus deferens. The ultrastructural morphology of these cells closely resembles that of the intraepithelial lymphocytes in the intestinal mucosa and those obtained from the lymph nodes, spleen blood and thoracic duct. The mucleus is spherical and is characterized by clumps of chromatin near the nuclear membrane. A thin rim of cytoplasm is usually found, and is remarkably free of most cell organelles except for free ribosomes. Frequently, a blunt cytoplasmic process can be seen extending from one end of the cell. Membrane-bounded granules and other dense bodies are occasionally encountered in the cytoplasm. The possible functional significance of intraepithelial lymphocytes in the male reproductive tract is discussed.
虽然淋巴细胞在“正常”生精上皮中从未出现，但在生精小管与直精小管交界处附近的生精小管末端可发现它们。睾丸直精小管、输出小管、附睾和输精管中也可发现上皮内淋巴细胞。这些细胞的超微结构形态与肠黏膜上皮内淋巴细胞以及从淋巴结、脾脏、血液和胸导管获取的淋巴细胞非常相似。细胞核呈球形，其特征是靠近核膜处有染色质团块。通常可见一薄层细胞质边缘，除游离核糖体外，几乎没有大多数细胞器。细胞一端常可见一个钝圆的细胞质突起。细胞质中偶尔可见膜结合颗粒和其他致密体。本文讨论了男性生殖道上皮内淋巴细胞可能的功能意义。
