14C脂肪吸收试验的临床评估
Clinical evaluation of the 14C fat absorption test.
作者信息
Burrows P J, Fleming J S, Garnett E S, Ackery D M, Colin-Jones D G, Bamforth J
出版信息
Gut. 1974 Feb;15(2):147-50. doi: 10.1136/gut.15.2.147.
Abstract
The absorption of (14)C-labelled glyceryl tripalmitate was tested in 62 patients by determining the maximum specific activity of CO(2) in the breath after an oral dose. A significant correlation with faecal fat excretion was found. The absorption of (14)C labelled palmitic acid was tested subsequently in 54 patients. In cases of pancreatic steatorrhoea, normal absorption of palmitic acid with impaired absorption of glyceryl tripalmitate was found, whereas in most patients with coeliac disease the absorption of both substances was depressed to the same extent.
摘要
通过测定口服剂量后呼出气体中二氧化碳的最大比活性，对62例患者进行了（14）C标记的三棕榈酸甘油酯吸收情况的测试。发现其与粪便脂肪排泄存在显著相关性。随后对54例患者进行了（14）C标记的棕榈酸吸收情况的测试。在胰腺性脂肪泻患者中，发现棕榈酸吸收正常但三棕榈酸甘油酯吸收受损，而在大多数乳糜泻患者中，两种物质的吸收均同等程度降低。
相似文献
1
Clinical evaluation of the 14C fat absorption test.14C脂肪吸收试验的临床评估
Gut. 1974 Feb;15(2):147-50. doi: 10.1136/gut.15.2.147.
2
The value of the 14C breath test in the assessment of fat absorption.
Scand J Gastroenterol. 1979;14(8):914-20.
3
The glyceryl [14C]tripalmitate breath test: a reassessment.甘油[14C]三棕榈酸酯呼气试验：重新评估
Clin Chim Acta. 1980 May 9;103(3):317-23. doi: 10.1016/0009-8981(80)90150-3.
4
Diagnosis of fat absorption with 14C-tripalmitate/3H-palmitic acid.用14C-三棕榈酸酯/3H-棕榈酸诊断脂肪吸收
Scand J Gastroenterol. 1979;14(5):587-92. doi: 10.3109/00365527909181394.
5
Measurement of fat absorption using [3H]glycerol triether and [14C]glycerol trioleate in man.使用[3H]甘油三醚和[14C]甘油三油酸酯对人体脂肪吸收进行测量。
Clin Chim Acta. 1980 May 9;103(3):325-34. doi: 10.1016/0009-8981(80)90151-5.
6
Xylose-1-14C absorption test: the use of urine, serum and breath analysis, and comparison with a colorimetric assay.木糖-1-¹⁴C吸收试验：尿液、血清和呼气分析的应用以及与比色测定法的比较。
Aust N Z J Med. 1976 Dec;6(6):532-6. doi: 10.1111/j.1445-5994.1976.tb03987.x.
7
[The 14C-tripalmitate test as a differential diagnostic method in resorption insufficiencies].[¹⁴C-三棕榈酸酯试验作为吸收功能不全的鉴别诊断方法]
Dtsch Z Verdau Stoffwechselkr. 1968;28(2):117-9.
8
9
Measurement of intestinal fat absorption with carbon-14 labeled tracers.
J Lab Clin Med. 1968 Mar;71(3):400-11.
10
Is the fat breath test effective in the diagnosis of fat malabsorption and pancreatic disease?脂肪呼气试验对脂肪吸收不良和胰腺疾病的诊断有效吗？
Digestion. 1978;18(1-2):77-85. doi: 10.1159/000198186.
引用本文的文献
1
Dominant lethal mutations induced by 14C in mice.
Experientia. 1981;37(9):948-9. doi: 10.1007/BF01971770.
2
Differential diagnosis of maldigestion and malabsorption of fat. II. Comparison of 131I-triolein with 14C-triolein in normal, pancreatic juice-deficient, short bowel and bile-deficient dogs.脂肪消化与吸收不良的鉴别诊断。II. 正常、胰液缺乏、短肠及胆汁缺乏犬中131I-三油酸甘油酯与14C-三油酸甘油酯的比较。
Jpn J Surg. 1981;11(4):272-6. doi: 10.1007/BF02468767.
3
Differential diagnosis of maldigestion and malabsorption of fat. I. Comparison of the radioactivity of triglyceride and non-esterified fatty acid in fecal fat using purified 131I-triolein.
Jpn J Surg. 1981;11(4):263-71. doi: 10.1007/BF02468766.
4
Metabolism of ingested 14C-triolein. Estimation of radiation dose in tests of lipid assimilation using 14C-and 3H-labelled fatty acids.摄入的14C-三油酸甘油酯的代谢。使用14C和3H标记脂肪酸进行脂质同化试验时辐射剂量的估算。
Eur J Nucl Med. 1981;6(7):327-9. doi: 10.1007/BF00262527.
5
Comparison of simple screening tests for fat malabsorption.脂肪吸收不良简易筛查试验的比较
Br Med J (Clin Res Ed). 1981 May 9;282(6275):1501-4. doi: 10.1136/bmj.282.6275.1501.
本文引用的文献
1
2
THE IMPURITY OF RADIOIODINATED TRIOLEIN.放射性碘化三油酸甘油酯的杂质
J Clin Pathol. 1964 Mar;17(2):160-2. doi: 10.1136/jcp.17.2.160.
3
Comparative fat and fatty acid intestinal absorption test utilizing radioiodine labeling; results in normal subjects.利用放射性碘标记的脂肪及脂肪酸肠道吸收比较试验；正常受试者的结果
Proc Soc Exp Biol Med. 1956 Jul;92(3):471-4. doi: 10.3181/00379727-92-22515.
4
Metabolic effects of oral neomycin.口服新霉素的代谢效应。
Clin Sci. 1967 Aug;33(1):111-24.
5
Measurement of tryptic activity in intestinal juice as a diagnostic test of pancreatic disease.测定肠液中的胰蛋白酶活性作为胰腺疾病的诊断试验。
Gut. 1967 Aug;8(4):408-14. doi: 10.1136/gut.8.4.408.
6
Measurement of intestinal fat absorption with carbon-14 labeled tracers.
J Lab Clin Med. 1968 Mar;71(3):400-11.
7
Bile-salt deconjugation and steatorrhoea in patients with the stagnant-loop syndrome.淤滞环综合征患者的胆汁盐去结合作用与脂肪泻
Lancet. 1968 Jul 6;2(7558):12-6. doi: 10.1016/s0140-6736(68)92888-2.
Zotero 插件