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三种血清学检测方法在淋球菌感染中的比较。

Comparison of three serological tests in gonococcal infection.

作者信息

Rodas C U, Ronald A R

出版信息

Appl Microbiol. 1974 Apr;27(4):695-8. doi: 10.1128/am.27.4.695-698.1974.

Abstract

Three serological tests used in the diagnosis of gonococcal infection were compared with cultural techniques in 857 females attending the Prenatal and Gynaecology Clinics at the Winnipeg General Hospital. The tests evaluated were the microflocculation technique (MFT), the indirect fluorescent-antibody technique (IFAT), and the complement-fixation technique (CFT). One hundred six patients had positive cultures for Neisseria gonorrhoeae. In this population, the MFT was reactive in 80 patients (75.4%), the IFAT was reactive in 74 (69.8%), and the CFT was reactive in 33 (31.1%). In the 751 patients with negative cultures, the MFT was positive in 11.4%, the IFAT was positive in 17.4%, and the CFT was positive in 10.5%. Sera from 9 of 10 patients with gonococcal arthritis were positive with the MFT.

摘要

在温尼伯总医院产前和妇科诊所就诊的857名女性中,将用于诊断淋球菌感染的三种血清学检测方法与培养技术进行了比较。所评估的检测方法为微量絮凝技术(MFT)、间接荧光抗体技术(IFAT)和补体结合技术(CFT)。106例患者淋病奈瑟菌培养呈阳性。在这组人群中,MFT在80例患者中呈阳性反应(75.4%),IFAT在74例患者中呈阳性反应(69.8%),CFT在33例患者中呈阳性反应(31.1%)。在751例培养阴性的患者中,MFT阳性率为11.4%,IFAT阳性率为17.4%,CFT阳性率为10.5%。10例淋球菌关节炎患者中有9例的血清MFT检测呈阳性。

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