Carlson K, Kozinski A W
J Virol. 1974 Jun;13(6):1274-90. doi: 10.1128/JVI.13.6.1274-1290.1974.
"Conservative phage" containing a genome derived from an infecting phage particle which has not undergone replication in the cell but nevertheless has become encapsulated and released in a normal phage particle, are found after infection of Escherichia coli with rII(-) or rI(-) mutants under conditions which result in rapid lysis. If such conservative phage are derived from a mixed infection with v(+) and v(1) phage, they display phenotypic mixing of the v gene product (an endonuclease carried in the phage particle). Populations of rI and rII mutant phage grown under conditions of rapid lysis include particles containing short DNA fragments. It is suggested that a "maturation defect", common to rI and rII mutants, but absent in rIII mutants, may account for the encapsulation of nonreplicated DNA as well as that of the DNA fragments.
“保守噬菌体”含有源自感染性噬菌体颗粒的基因组，该基因组在细胞中未进行复制，但仍被包裹并以正常噬菌体颗粒的形式释放，在用rII（ - ）或rI（ - ）突变体感染大肠杆菌后，在导致快速裂解的条件下被发现。如果这种保守噬菌体源自v（ + ）和v（1）噬菌体的混合感染，它们会表现出v基因产物（噬菌体颗粒中携带的一种内切核酸酶）的表型混合。在快速裂解条件下生长的rI和rII突变噬菌体群体包括含有短DNA片段的颗粒。有人提出，rI和rII突变体共有的“成熟缺陷”，但rIII突变体中不存在，可能解释了未复制DNA以及DNA片段的包裹现象。
