来自“不可培养”分枝杆菌的霉菌酸
Mycolic acids from "noncultivable" mycobacteria.
作者信息
Etemadi A H, Convit J
出版信息
Infect Immun. 1974 Jul;10(1):236-9. doi: 10.1128/iai.10.1.236-239.1974.
Abstract
Chromatographic analysis, coupled to mass spectrometry with a high-resolution mass spectrometer, of materials isolated from skin lesions of patients with lepromatous leprosy allows the recognition of characteristic mycobacterial products, mycolic acids. This finding indicates that the "noncultivable" bacteria responsible for leprosy are mycobacteria.
摘要
通过使用高分辨率质谱仪与质谱联用的色谱分析法，对麻风瘤型麻风患者皮肤病变中分离出的物质进行分析，能够识别出特征性的分枝杆菌产物——分枝菌酸。这一发现表明，导致麻风病的“不可培养”细菌是分枝杆菌。
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引用本文的文献
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本文引用的文献
1
[Mycolic acids. Structure, biogenesis and phylogenetic value].
Expos Annu Biochim Med. 1967;28:77-109.
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Identification of the noncultivable pathogenic mycobacteria M. leprae and M. lepraemurium.
Int J Lepr Other Mycobact Dis. 1968 Apr-Jun;36(2):166-70.
3
[Structural and biogenetic correlations of mycolic acids in relation to the phylogenesis of various genera of Actinomycetales].[分枝菌酸的结构及生物发生与放线菌目各属系统发育的相关性]
Bull Soc Chim Biol (Paris). 1967;49(6):695-706.
4
Cytochemical reactions of human leprosy bacilli and mycobacteria: ultrastructural implications.人类麻风杆菌和分枝杆菌的细胞化学反应：超微结构方面的意义
J Bacteriol. 1973 Mar;113(3):1389-99. doi: 10.1128/jb.113.3.1389-1399.1973.
5
Elimination of the acid fastness but not the gram positivity of leprosy bacilli after extraction with pyridine.用吡啶提取后，麻风杆菌的抗酸性消失，但革兰氏阳性特性未消失。
J Bacteriol. 1971 May;106(2):707-8. doi: 10.1128/jb.106.2.707-708.1971.
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