吸入性倍氯米松与口腔念珠菌病。
Inhaled beclomethasone and oral candidiasis.
作者信息
Shaw N J, Edmunds A T
出版信息
Arch Dis Child. 1986 Aug;61(8):788-90. doi: 10.1136/adc.61.8.788.
Abstract
Two hundred and twenty nine children aged 6 to 15 years attending the asthma clinic at the Royal Hospital for Sick Children, Edinburgh, had throat swabs taken to determine the incidence of candida colonisation of the oropharynx. One hundred children (group A), who were not receiving steroids, were compared with 91 children (group B) receiving less than 500 micrograms of inhaled beclomethasone a day and 38 children (group C) receiving 500 micrograms or more of inhaled beclomethasone a day. Sore throat and hoarse voice were not related to the presence of candida or to treatment with inhaled steroids. The incidence of candida was greater in the groups given treatment with steroids but did not increase at a higher dosage, nor was it related to the type of inhaler used. There was only one case of clinical thrush in all the children studied.
摘要
229名6至15岁的儿童前往爱丁堡皇家儿童医院哮喘诊所就诊，他们接受了咽拭子检查，以确定口咽念珠菌定植的发生率。100名未接受类固醇治疗的儿童（A组）与91名每天吸入少于500微克倍氯米松的儿童（B组）以及38名每天吸入500微克或更多倍氯米松的儿童（C组）进行了比较。喉咙痛和声音嘶哑与念珠菌的存在或吸入类固醇治疗无关。接受类固醇治疗的组中念珠菌的发生率更高，但在更高剂量下并未增加，也与所使用的吸入器类型无关。在所有研究的儿童中仅出现1例临床鹅口疮病例。
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