Surwit E A, Joelsson I, Einhorn N
Obstet Gynecol. 1981 Nov;58(5):590-5.
One hundred fifty-two patients with stage I, grades 2 and 3 adenocarcinoma of the endometrium, treated in 1972 and 1973 at the Radiumhemmet, are presented. Two uterine packings followed at 4 to 6 weeks by total abdominal hysterectomy and bilateral salpingo-oophorectomy resulted in a 5-year survival of 89%, whereas patients treated primarily with surgery followed by vaginal cylinder irradiation demonstrated 90% survival. Patients in both groups received whole pelvis irradiation postoperatively for deep myometrial invasion (more than 50% invasion by viable tumor). Patients treated with radiation therapy alone had 57% survival. Optimal results in poorly differentiated (grade 3) carcinoma of the endometrium were achieved with preoperative packings (90% survival); only 12% of the patients required external radiation therapy postoperatively.
本文介绍了1972年至1973年在镭疗中心接受治疗的152例I期2级和3级子宫内膜腺癌患者。采用两次子宫填塞，4至6周后行全腹子宫切除术和双侧输卵管卵巢切除术，5年生存率为89%；而主要接受手术治疗，随后行阴道柱状照射的患者生存率为90%。两组患者若存在深肌层浸润（存活肿瘤浸润超过50%），术后均接受全盆腔照射。单纯接受放射治疗的患者生存率为57%。术前填塞治疗子宫内膜低分化（3级）癌取得了最佳效果（生存率90%）；仅12%的患者术后需要接受外照射治疗。
