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孕期风疹抗体滴度呈阳性:有效性问题。

Positive rubella titers in pregnancy: a question of validity.

作者信息

Hall J A, Wills E R, Hall K, Pearson J W

出版信息

Obstet Gynecol. 1979 Aug;54(2):235-6.

PMID:460760
Abstract

A review of 25 patients with more than 1 rubella titer by hemagglutination-inhibition testing revealed 3 patients with high positive titers that were reported to be negative in subsequent pregnancies. None of the patients had received the rubella vaccine. Because the sensitivity and reliability of hemagglutination-inhibition testing is markedly influenced by multiple variables, it is important for both the clinician and the pathologist to be aware of both the limitations of the testing method and the meaning of an antibody titer on a single isolated specimen.

摘要

通过血凝抑制试验对25名风疹滴度超过1的患者进行回顾发现,有3名患者风疹滴度呈强阳性,但在随后的妊娠检查中却报告为阴性。所有患者均未接种风疹疫苗。由于血凝抑制试验的敏感性和可靠性受到多种变量的显著影响,因此临床医生和病理学家都必须清楚该检测方法的局限性以及单个独立样本抗体滴度的意义。

相似文献

1
Positive rubella titers in pregnancy: a question of validity.孕期风疹抗体滴度呈阳性:有效性问题。
Obstet Gynecol. 1979 Aug;54(2):235-6.
2
Rubella antibody titer. The significance of low-titered rubella antibodies.风疹抗体滴度。低滴度风疹抗体的意义。
Obstet Gynecol. 1978 Aug;52(2):243-5.
3
[Seroconversion in rubella HI titers during pregnancy].[孕期风疹血凝抑制抗体滴度的血清学转换]
Fortschr Med. 1978 Jan 5;96(1):17-20.
4
How to diagnose rubella during pregnancy.如何在孕期诊断风疹。
Am Fam Physician. 1981 Feb;23(2):205-8.
5
[Serologic rubella diagnosis. The determination of minimal rubella antibody levels].
Fortschr Med. 1981 Jul 2;99(25):986-90.
6
Maternal rubella and its virological diagnosis.孕妇风疹及其病毒学诊断。
Postgrad Med J. 1972 Jul;48:Suppl 3:11-7.
7
[Rubella immunity among a group of pregnant women of the Montreal region: implications for vaccination].[蒙特利尔地区一组孕妇的风疹免疫力:对疫苗接种的影响]
Union Med Can. 1973 May;102(5):1104-7.
8
Prolonged rubella IgM antibody response.风疹IgM抗体反应延长。
Med J Aust. 1974 Oct 26;2(17):629-31.
9
Clinical rubella reinfection during pregnancy in a previously vaccinated woman.一名曾接种过疫苗的女性在孕期发生临床风疹再感染。
J Infect. 2000 Sep;41(2):187-9. doi: 10.1053/jinf.2000.0716.
10
[Method and quality control of the rubella hemagglutination inhibition test].风疹血凝抑制试验的方法与质量控制
Z Gesamte Hyg. 1988 Apr;34(4):258-61.

引用本文的文献

1
Nonspecific reactions in the hemagglutination inhibition test for detection of rubella antibodies.用于检测风疹抗体的血凝抑制试验中的非特异性反应。
J Clin Microbiol. 1981 May;13(5):818-23. doi: 10.1128/jcm.13.5.818-823.1981.
2
Comparison of the latex agglutination test with the hemagglutination inhibition test, enzyme-linked immunosorbent assay, and neutralization test for detection of antibodies to rubella virus.乳胶凝集试验与血凝抑制试验、酶联免疫吸附测定及中和试验在检测风疹病毒抗体方面的比较。
J Clin Microbiol. 1982 Oct;16(4):644-9. doi: 10.1128/jcm.16.4.644-649.1982.
3
Obstetric infections.
产科感染
West J Med. 1981 May;134(5):394-404.
4
Congenital rubella affecting an infant whose mother had rubella antibodies before conception.先天性风疹影响一名母亲在受孕前就有风疹抗体的婴儿。
Br Med J (Clin Res Ed). 1981 Apr 11;282(6271):1235-6. doi: 10.1136/bmj.282.6271.1235-a.