Harris R E, Jordon P A, Monif G R
Obstet Gynecol. 1978 Aug;52(2):243-5.
The hemagglutination inhibition (HAI) test is not mathematically precise and reproducible. Thus, it is critical to know whether or not the threshold titer (1 : 10) of detectable rubella antibody is indicative of true immunity. Three patients with a 1 : 10 HAI titer presented with subsequent rubella during gestation. Ninety postpartum patients with a HAI titer of 1 : 10 were vaccinated and the rubella antibody titers were reassessed. Seventeen percent of these patients responded to the vaccine challenge with an eightfold or greater rise in titer. Thus, we recommend that the patient with a low HAI titer (1 : 10) should be considered to have marginal immunity to rubella and should be vaccinated.
血凝抑制（HAI）试验在数学上并不精确且缺乏可重复性。因此，了解可检测到的风疹抗体阈值效价（1:10）是否表明真正的免疫力至关重要。三名HAI效价为1:10的患者在妊娠期随后出现了风疹。对90名HAI效价为1:10的产后患者进行了疫苗接种，并重新评估了风疹抗体效价。这些患者中有17%对疫苗激发产生了效价升高八倍或更高的反应。因此，我们建议HAI效价低（1:10）的患者应被视为对风疹具有边缘免疫力，应进行疫苗接种。
