Kalbfleisch J G, Sprott D A
J Hyg (Lond). 1974 Aug;73(1):27-34. doi: 10.1017/s0022172400023792.
Methods of statistical analysis are presented for one or more dilution series experiments where the quantity of interest is the number of virus particles required to infect a cell. These methods are illustrated on several data sets drawn from the literature. Data from seven series, which have been used to support a two-particle model in the literature, are here shown to reject such a model decisively, whereas fifteen other experiments are found to be in excellent agreement with a one-particle model.
本文介绍了用于一个或多个稀释系列实验的统计分析方法,这些实验中关注的量是感染一个细胞所需的病毒颗粒数量。这些方法通过从文献中提取的几个数据集进行了说明。文献中曾用于支持双颗粒模型的七个系列的数据,在此被证明果断地否定了该模型,而其他十五个实验则被发现与单颗粒模型高度吻合。