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多发性硬化症患者脑脊液中麻疹病毒特异性IgG

Measles virus-specific IgG in cerebrospinal fluid in multiple sclerosis.

作者信息

Haire M, Millar J H, Merrett J D

出版信息

Br Med J. 1974 Oct 26;4(5938):192-3. doi: 10.1136/bmj.4.5938.192.

Abstract

The prevalence of measles virus-specific IgG in cerebrospinal fluid (C.S.F.) of patients with multiple sclerosis (M.S.) has been compared with that in fluids from patients with other neurological diseases and from normal control subjects. The prevalence in the three groups was 58.1%, 24.1%, and 0% respectively. Fivefold concentration of the specimens increased the prevalence in the first two groups to 80.6% and 34.5% respectively, while measles IgG was not detected in any fluids of the normal control group, even after concentration.

摘要

已将多发性硬化症(MS)患者脑脊液(C.S.F.)中麻疹病毒特异性IgG的患病率与其他神经系统疾病患者及正常对照受试者的脑脊液患病率进行了比较。三组的患病率分别为58.1%、24.1%和0%。样本浓度提高五倍后,前两组的患病率分别升至80.6%和34.5%,而正常对照组的任何脑脊液样本中均未检测到麻疹IgG,即使在浓缩后也是如此。

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