Canivet B, Krebs B P, Bonet C, Aubanel J M, Blaive B, Lalanne C M
Nouv Presse Med. 1979 Mar 3;8(10):747-50.
Determination of carcinoembryonic antigen (CEA) by radioimmunoassay was performed in per-endoscopic obtained bronchial secretion. Bronchial CEA values are higher in the case of primary carcinoma of the lung than of metastatic lung cancer or pulmonary benign disease (p less than 0.0005). More interesting is the ratio bronchial CEA/serum CEA which is much higher in primary carcinoma of the lung than in benign disease (p less than 0.0005) and lower in metastatic lung carcinoma than benign disease (p less than 0.0025). In primary carcinoma of the lung, the CEA determination seems to have a prognostic value since higher levels are reported in patients unsuccessfully treated than in treated patients with apparent remission.
采用放射免疫分析法对经内镜获取的支气管分泌物进行癌胚抗原(CEA)检测。肺癌原发性癌患者的支气管CEA值高于转移性肺癌或肺部良性疾病患者(p<0.0005)。更有意思的是支气管CEA/血清CEA比值,该比值在肺癌原发性癌患者中远高于良性疾病患者(p<0.0005),而在转移性肺癌患者中低于良性疾病患者(p<0.0025)。在肺癌原发性癌中,CEA检测似乎具有预后价值,因为据报道,治疗未成功的患者CEA水平高于病情明显缓解的接受治疗患者。