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[内侧基底下丘脑5-羟色胺受体在垂体-睾丸复合体负反馈机制中的作用]

[Role of serotonin receptors of the medial-basal hypothalamus in the mechanisms of negative feedback of the hypophyseal-testicular complex].

作者信息

Naumenko E V, Shishkina G T

出版信息

Probl Endokrinol (Mosk). 1979 May-Jun;25(3):49-52.

PMID:461383
Abstract

Administration of serotonin into the lateral ventricle of the brain of male rats, against the background of complete isolation of the medial-basal hypothalamus was accompanied by the block of the compensatory elevation of the blood testosterone level following unilateral castration. Experiments with local serotonin administration into the hypophysial region of the hypothalamus of hemicastrated rats indicated that the inhibitory effect produced by the excitation of the serotonin receptors of this region on the mechanism of the negative feedback of the hypophysis-testicular system was realized at the arcuate nuclei level.

摘要

在完全隔离内侧基底下丘脑的背景下，向雄性大鼠脑侧脑室注射血清素，伴随着单侧去势后血液睾酮水平代偿性升高的阻断。对半阉割大鼠下丘脑垂体区域进行局部血清素注射的实验表明，该区域血清素受体兴奋对垂体-睾丸系统负反馈机制产生的抑制作用是在弓状核水平实现的。

相似文献

1
[Role of serotonin receptors of the medial-basal hypothalamus in the mechanisms of negative feedback of the hypophyseal-testicular complex].[内侧基底下丘脑5-羟色胺受体在垂体-睾丸复合体负反馈机制中的作用]
Probl Endokrinol (Mosk). 1979 May-Jun;25(3):49-52.
2
[Participation of the cerebral serotonin receptors in the negative-feedback mechanisms of the hypothalamus-hypophysis-testis system].[大脑血清素受体在下丘脑-垂体-睾丸系统负反馈机制中的作用]
Probl Endokrinol (Mosk). 1977 Mar-Apr;23(2):75-8.
3
Role of serotonin in feedback control of hypothalamic-pituitary-testicular complex in male rats.血清素在雄性大鼠下丘脑-垂体-睾丸复合体反馈控制中的作用。
Neuroendocrinology. 1978;26(6):359-66. doi: 10.1159/000122791.
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The participation of serotonin receptors of the brain in mechanisms of negative feedback of the hypothalamus-pituitary-testis system.大脑中血清素受体在下丘脑-垂体-睾丸系统负反馈机制中的参与。
Neurosci Behav Physiol. 1978 Jul-Sep;9(3):227-9. doi: 10.1007/BF01187177.
5
Hypothalamic serotoninergic receptors in negative feed-back regulation of pituitary-testicular axis in rats.大鼠垂体-睾丸轴负反馈调节中的下丘脑5-羟色胺能受体
Endocrinol Exp. 1980 Sep;14(3):207-13.
6
[Interaction central GABA-B receptors with serotoninergic brain system during regulation of the hypothalamo-hypophyseal-testicular axis by the negative feedback mechanism in rats].
Ross Fiziol Zh Im I M Sechenova. 1998 May-Jun;84(5-6):474-9.
7
[The interaction of GABA-A receptors with the serotoninergic system of the brain in regulating the testosterone level by the negative feedback mechanism].[γ-氨基丁酸A受体与大脑5-羟色胺能系统通过负反馈机制调节睾酮水平的相互作用]
Fiziol Zh Im I M Sechenova. 1996 Oct-Nov;82(10-11):84-90.
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Fiziol Zh SSSR Im I M Sechenova. 1988 Jun;74(6):798-801.
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[Role of various types of serotonin reception in the hypothalamic modulation of the release of luteinizing hormone].
Fiziol Zh SSSR Im I M Sechenova. 1986 Mar;72(3):316-22.
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Probl Endokrinol (Mosk). 1980 Mar-Apr;26(2):53-7.