Harrison C V
J Clin Pathol. 1972 Jan;25(1):12-6. doi: 10.1136/jcp.25.1.12.
In 16 cases of Waldenström's macroglobulinaemia the following findings were sufficiently frequent to justify a provisional diagnosis: a modestly enlarged node with lymphocytic infiltration through the capsule into the adjacent connective tissue, retention of the sinus and medullary reticulin pattern, few or no peripheral follicles, sinuses marked out by pale histiocytes, scanty mitoses, numerous plasma cells, and dark staining of plasma in blood vessels. Mast cells were not more frequent than in reactive nodes, but were more frequent than in lymphomas. Periodic acid-Schiff-positive inclusions were found in every case, but were usually very scanty. Similar inclusions can rarely be found in other cases.
在16例瓦尔登斯特伦巨球蛋白血症患者中，以下表现出现的频率足以支持初步诊断：淋巴结轻度肿大，淋巴细胞浸润穿过包膜进入相邻结缔组织，窦和髓质网状纤维结构保留，外周滤泡少或无，窦由淡染组织细胞界定，有丝分裂少，浆细胞多，血管内血浆染色深。肥大细胞出现的频率不比反应性淋巴结高，但比淋巴瘤高。每例均发现有过碘酸希夫阳性包涵体，但通常很少。在其他病例中很少能发现类似的包涵体。
