Zuckerman A J, Baines P M, Almeida J D
Nature. 1972 Mar 10;236(5341):78-81. doi: 10.1038/236078a0.
ATTEMPTS to isolate the human hepatitis viruses in tissue culture have resulted in a collection of “hepatitis-candidate” viruses, none of which has since been shown to be the causal agent of human hepatitis. The discovery of Australia antigen provided a specific serological marker of infection with or carriage of the serum hepatitis virus, although the nature of the antigen remains unsettled.
在组织培养中分离人类肝炎病毒的尝试已产生了一批“候选肝炎”病毒,但此后没有一种被证明是人类肝炎的病原体。澳大利亚抗原的发现为血清型肝炎病毒感染或携带提供了一种特异性血清学标志物,尽管该抗原的性质仍未明确。