PLC/PRF/5（亚历山大）肝癌细胞系：进一步的特性鉴定及感染性研究。
PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity.
作者信息
Daemer R J, Feinstone S M, Alexander J J, Tully J G, London W T, Wong D C, Purcell R H
出版信息
Infect Immun. 1980 Nov;30(2):607-11. doi: 10.1128/iai.30.2.607-611.1980.
Abstract
The Alexander hepatoma cell line, PLC/PRF/5, was studied for evidence of hepatitis B virus markers and alpha-fetoprotein. Only hepatitis B surface antigen and alpha-fetoprotein were detected. Induction experiments with 5-iodo-2'-deoxyuridine and inoculation of chimpanzees with whole cells or tissue culture fluid did not reveal evidence of synthesis of additional hepatitis B virus markers or of production of infectious virus.
摘要
对亚历山大肝癌细胞系PLC/PRF/5进行了研究，以寻找乙肝病毒标志物和甲胎蛋白的证据。仅检测到乙肝表面抗原和甲胎蛋白。用5-碘-2'-脱氧尿苷进行诱导实验，以及用全细胞或组织培养液接种黑猩猩，均未发现合成其他乙肝病毒标志物或产生传染性病毒的证据。
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