Worthen D M
Surv Ophthalmol. 1979 May-Jun;23(6):403-6. doi: 10.1016/0039-6257(79)90236-4.
The practical value of any therapy depends upon a combination of effectiveness of the agent (or procedure) and the extent to which the patient complies in its proper administration. Thus, it might be said that the multiple of effectiveness times compliance equals the "usefulness product." Among the various glaucoma therapies, this product seems to range from about 30%--90%. Timolol's effectiveness in lowering intraocular pressure combined with its low incidence of side effects yields a high usefulness product, and this may decrease the incidence of surgery required for the treatment of the open-angle glaucomas.
任何治疗方法的实际价值取决于药物（或治疗程序）的有效性以及患者在正确使用时的依从程度。因此，可以说有效性乘以依从性的结果等于“有用性乘积”。在各种青光眼治疗方法中，这个乘积似乎在30%至90%之间。噻吗洛尔降低眼压的有效性及其较低的副作用发生率产生了较高的有用性乘积，这可能会降低开角型青光眼治疗所需的手术发生率。
