Wei P, Hamilton J R, LeBlanc A E
Can Med Assoc J. 1972 May 6;106(9):969-74 passim.
Two commercially available, high-caloric intravenous solutions were given as the sole source of calories to 23 children (aged three weeks to 17 years), all gravely ill and unable to ingest untrients, for one to 12 weeks. All but one survived, gained weight, remained in positive nitrogen balance and resumed taking adequate diets by mouth.The patients utilized sugar, amino acids and fats efficiently without abnormalities of kidney and liver function. Septicemia developed in six of 15 patients receiving solution by central venous catheter. Those receiving infusion by peripheral vein only, eight of 23, remained infection-free.The procedure is safe if serum electrolytes are constantly and meticulously monitored and is a useful adjunct to the treatment of children unable to eat.
两种市售的高热量静脉内溶液作为唯一的热量来源,给予23名儿童(年龄从3周大至17岁),这些儿童均病情严重且无法摄取营养物质,持续一至十二周。除一名儿童外,其他所有儿童均存活下来,体重增加,保持正氮平衡,并恢复经口摄入充足饮食。患者能有效利用糖、氨基酸和脂肪,且肝肾功能无异常。15名通过中心静脉导管接受溶液的患者中有6人发生败血症。仅通过外周静脉输液的患者中,23人中有8人未发生感染。如果能持续且细致地监测血清电解质,该方法是安全的,并且是治疗无法进食儿童的一种有用辅助手段。