急性传染性肝炎和血清性肝炎中的补体水平。
Complement levels in acute infectious hepatitis and serum hepatitis.
作者信息
Kosmidis J C, Leader-Williams L K
出版信息
Clin Exp Immunol. 1972 May;11(1):31-5.
Abstract
The level of the third component of complement was measured in serial specimens of serum taken from thirty-one patients with acute viral hepatitis. Fourteen of the thirty-one patients were positive for the hepatitis-associated antigen. A characteristic fluctuation was observed in twenty-nine of the thirty-one patients. This consisted of an initial fall of the level of C3, followed by an increase to a higher than normal level and then a gradual return to normal. No difference was observed between the patients who were positive and those who were negative for the hepatitis-associated antigen. These results support the view that immune complexes play a significant role in the pathogenesis of acute viral hepatitis.
摘要
对31例急性病毒性肝炎患者的系列血清标本进行补体第三成分水平测定。31例患者中有14例肝炎相关抗原呈阳性。31例患者中有29例观察到特征性波动。表现为C3水平先下降，随后升高至高于正常水平，然后逐渐恢复正常。肝炎相关抗原阳性和阴性的患者之间未观察到差异。这些结果支持免疫复合物在急性病毒性肝炎发病机制中起重要作用这一观点。
相似文献
1
Complement levels in acute infectious hepatitis and serum hepatitis.急性传染性肝炎和血清性肝炎中的补体水平。
Clin Exp Immunol. 1972 May;11(1):31-5.
2
Hepatitis: intrahepatic expression of Au antigen and immune complexes in liver tissue.肝炎：肝组织中Au抗原的肝内表达及免疫复合物。
Vox Sang. 1973;24:Suppl:27-32. doi: 10.1111/j.1423-0410.1973.tb03509.x.
3
[Behavior of the serum concentration of the C3 component of complement during viral hepatitis].[病毒性肝炎时补体C3成分血清浓度的变化]
Boll Ist Sieroter Milan. 1971 Mar-Apr;50(2):95-8.
4
[Immune complexes in viral hepatitis. Fulminating hepatitis].[病毒性肝炎中的免疫复合物。暴发性肝炎]
Nouv Presse Med. 1972 Jun 24;1(26):1763-8.
5
[Clinical significance of hepatitis B-antigen].[乙肝抗原的临床意义]
Internist (Berl). 1973 Nov;14(11):554-63.
6
Haemolytic complement anticomplementary activity and hepatitis-B antigen in sera of patients with acute hepatitis.急性肝炎患者血清中的溶血补体抗补体活性及乙型肝炎抗原
Indian J Med Res. 1974 Apr;62(4):534-8.
7
Detection of Australia-SH antigen in serum. A comparison of the electron microscopical, agar gel double diffusion, and complement fixation tests.血清中澳大利亚-SH抗原的检测。电子显微镜检查、琼脂凝胶双向扩散试验及补体结合试验的比较。
Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Apr;82(2):151-63.
8
Immunohistochemical studies of liver tissues.肝脏组织的免疫组织化学研究。
Pathol Eur. 1972;7(3):299-306.
9
Comparison of complement--fixation and immunodiffusion tests for the detection of hepatitis-associated antigen.用于检测肝炎相关抗原的补体结合试验与免疫扩散试验的比较。
Pathol Microbiol (Basel). 1972;38(5):346-53. doi: 10.1159/000162434.
10
[Australia antigen. Present data].[澳大利亚抗原。现有数据]
Ann Biol Clin (Paris). 1970;28(4):287-94.
引用本文的文献
1
Immune complexes in human diseases: a review.人类疾病中的免疫复合物：综述
Am J Pathol. 1980 Aug;100(2):529-94.
2
Studies on circulating immune complexes of the liver disease. 4. Clq binding activity.肝脏疾病循环免疫复合物的研究。4. Clq结合活性。
Gastroenterol Jpn. 1980;15(1):27-32. doi: 10.1007/BF02773701.
3
Serum complement in chronic liver disease.慢性肝病中的血清补体
Gut. 1973 Jun;14(6):451-6. doi: 10.1136/gut.14.6.451.
4
Serum immunoglobulins, complement component levels and autoantibodies in liver disease.肝病患者的血清免疫球蛋白、补体成分水平及自身抗体
Clin Exp Immunol. 1973 Jul;14(3):335-46.
5
Problems of bacterial infection in patients with liver disease.肝病患者的细菌感染问题。
Gut. 1987 May;28(5):623-41. doi: 10.1136/gut.28.5.623.
6
Immune reactions in acute viral hepatitis.急性病毒性肝炎中的免疫反应。
Clin Exp Immunol. 1975 Apr;20(1):17-28.
7
Acute hepatitis: significance of changes in complement components.急性肝炎：补体成分变化的意义
Clin Exp Immunol. 1977 Jun;28(3):496-501.
8
Immune complexes in acute and chronic liver disease.急慢性肝病中的免疫复合物
Clin Exp Immunol. 1978 Feb;31(2):150-7.
9
HBsAg immune complexes in the course of infection with hepatitis B virus.乙型肝炎病毒感染过程中的乙肝表面抗原免疫复合物
Clin Exp Immunol. 1979 Jun;36(3):371-8.
10
Tropical cirrhosis and hepatoma.热带性肝硬化与肝癌
J R Coll Physicians Lond. 1976 Jan;10(2):133-44.
本文引用的文献
1
THE COMPLEMENT CONTENT OF HUMAN SERA WITH ESPECIAL REFERENCE TO MALARIA.人体血清中的补体含量，特别是与疟疾的关系
J Clin Invest. 1948 May;27(3 Pt 1):320-6. doi: 10.1172/JCI101960.
2
Serum complement levels in systemic lupus erythematosus and other diseases.系统性红斑狼疮及其他疾病中的血清补体水平
Australas Ann Med. 1960 Feb;9:57-63. doi: 10.1111/imj.1960.9.1.57.
3
Serum complement in hepatobiliary diseases.肝胆疾病中的血清补体
Proc Soc Exp Biol Med. 1955 Dec;90(3):606-8. doi: 10.3181/00379727-90-22111.
4
The significance of the complement test in liver diseases with jaundice.补体试验在黄疸型肝病中的意义。
Acta Med Scand. 1953;144(4):268-74. doi: 10.1111/j.0954-6820.1953.tb15696.x.
5
[On the behavior of some factors of natural immunity in the course of viral hepatitis].[关于病毒性肝炎病程中自然免疫某些因素的行为]
Epatologia. 1966 Jul-Aug;12(4):800-5.
6
[Serum complement in various acute and chronic liver diseases].[各种急慢性肝病中的血清补体]
G Clin Med. 1970 May;51(5):411-23.
7
Complement and immune complex. Molecular anatomy and function of C3 molecule on antigen-antibody complex.补体与免疫复合物。抗原抗体复合物上C3分子的分子结构与功能。
Folia Allergol (Roma). 1970 Jul-Aug;17(4):427.
8
The serum concentration of the third component of complement beta-1C-beta-1A in liver disease.肝病中补体β-1C-β-1A第三成分的血清浓度。
Gut. 1971 Jul;12(7):574-8. doi: 10.1136/gut.12.7.574.
9
The pathogenesis of arthritis associated with viral hepatitis. Complement-component studies.与病毒性肝炎相关的关节炎的发病机制。补体成分研究。
N Engl J Med. 1971 Jul 22;285(4):185-9. doi: 10.1056/NEJM197107222850401.
10
A complement-fixation test for measuring Australia antigen and antibody.一种用于检测澳大利亚抗原和抗体的补体结合试验。
J Infect Dis. 1969 Sep;120(3):383-6. doi: 10.1093/infdis/120.3.383.
Zotero 插件