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用高渗柠檬酸盐溶液保存缺血损伤的犬肾:甘露醇的重要性。

Preservation of ischaemically injured canine kidneys with hypertonic citrate solution: the importance of mannitol.

作者信息

Pentlow B D, Kostakis A J, Wall W J, Baker P G, Smith D P, Calne R Y

出版信息

Transplantation. 1979 Feb;27(2):99-101. doi: 10.1097/00007890-197902000-00006.

Abstract

The ability of hypertonic citrate solution to preserve ischaemically injured canine kidneys was investigated. It was found that if mannitol was given i.v. before ischaemia and again after graft revascularization, kidneys subjected to 30 min of warm ischaemia could be preserved for 24 hr, maintaining immediate life-sustaining function.

摘要

研究了高渗柠檬酸盐溶液对缺血损伤犬肾的保存能力。结果发现,如果在缺血前静脉注射甘露醇,移植肾血管再通后再次注射,经历30分钟热缺血的肾脏可保存24小时,并维持即刻维持生命的功能。

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