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基于临床遗传学研究数据的精神分裂症预后分析

On schizophrenia prognosis based on data of a clinicogenetical study.

作者信息

Kornetov A N, Majburd E D, Samokhvalov V P

出版信息

Tsitol Genet. 1979 Mar-Apr;13(2):136-40.

PMID:462533
Abstract

Peculiarities of the clinical picture of schizophrenia were studied in a group of patients in which less than a half (785) patients had the aggravating fact and in two hereditary-aggravated groups: siblings (109 patients) and parents--children (118 pairs). Prognostic significance of the genetic factor, sex and age was studied as related to peculiarities of the clinical picture of schizophrenia. Hereditary aggravation is shown to be of a decisive importance for schizophrenia prognosis.

摘要

在一组患者中研究了精神分裂症临床表现的特点,其中不到一半(785例)患者存在加重因素,并在两个遗传加重组中进行了研究:兄弟姐妹组(109例患者)和父母-子女组(118对)。研究了遗传因素、性别和年龄与精神分裂症临床表现特点相关的预后意义。结果表明,遗传加重对精神分裂症预后具有决定性意义。

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[Concordance of clinical signs of schizophrenia in families with hereditary loading].
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(9):1359-64.
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[Gender differences in schizophrenia].
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