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B组虫媒病毒感染后的人免疫球蛋白特异性

Human immunoglobulin specificity after group B arbovirus infections.

作者信息

Scott R M, McCown J M, Russell P K

出版信息

Infect Immun. 1972 Sep;6(3):277-81. doi: 10.1128/iai.6.3.277-281.1972.

Abstract

Sera obtained during a dengue-2 epidemic from individuals with primary or secondary group B arbovirus infections contained cross-reactive antibody against several viruses in this group. Hemagglutination-inhibition antibody titers of the immunoglobulin M fractions from these sera revealed a rise in antibody specific for dengue-2. The acute and convalescent sera in over half of the secondary infection group also had low-level unchanging immunoglobulin M antibody titers to yellow fever which implicated yellow fever immunization as the primary infection.

摘要

在登革热2型疫情期间从患有原发性或继发性B组虫媒病毒感染的个体获得的血清中含有针对该组中几种病毒的交叉反应抗体。这些血清中免疫球蛋白M组分的血凝抑制抗体滴度显示出针对登革热2型的特异性抗体升高。超过一半的继发性感染组的急性期和恢复期血清对黄热病也有低水平且不变的免疫球蛋白M抗体滴度,这表明黄热病免疫接种是原发性感染。

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