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感染甲病毒的人类体内的复杂特异性免疫球蛋白M抗体模式。

Complex-specific immunoglobulin M antibody patterns in humans infected with alphaviruses.

作者信息

Calisher C H, el-Kafrawi A O, Al-Deen Mahmud M I, Travassos da Rosa A P, Bartz C R, Brummer-Korvenkontio M, Haksohusodo S, Suharyono W

出版信息

J Clin Microbiol. 1986 Jan;23(1):155-9. doi: 10.1128/jcm.23.1.155-159.1986.

Abstract

Sera from humans with serologically confirmed eastern equine encephalitis, western equine encephalitis, Pogosta (Ockelbo), Mayaro, Ross River, and chikungunya virus infections were tested by immunoglobulin M (IgM) antibody capture enzyme immunoassay. Diagnostically useful IgM antibody titers were detected, and selected sera with high IgM antibody titers were tested for IgM antibody with nine heterologous alphaviruses. The results provide evidence for the complex specificity of IgM antibody and indicate the usefulness of this test in both individual cases and epidemic situations.

摘要

通过免疫球蛋白M(IgM)抗体捕获酶免疫测定法对血清学确诊的东部马脑炎、西部马脑炎、波戈斯塔(奥克尔博)、马亚罗、罗斯河和基孔肯雅病毒感染患者的血清进行检测。检测到具有诊断价值的IgM抗体滴度,并对选择的高IgM抗体滴度血清与9种异源甲病毒进行IgM抗体检测。结果为IgM抗体的复杂特异性提供了证据,并表明该检测在个体病例和疫情情况下均有用。

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