Anti-inflammatory and pharmacokinetic properties of sudoxicam N-(2-thiazolyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide.

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超能文献

作者信息

Wiseman E H, Chiaini J

出版信息

Biochem Pharmacol. 1972 Sep 1;21(17):2323-34. doi: 10.1016/0006-2952(72)90383-8.

DOI:10.1016/0006-2952(72)90383-8

PMID:4630489

Abstract

摘要

相似文献

Anti-inflammatory and pharmacokinetic properties of sudoxicam N-(2-thiazolyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide.

Biochem Pharmacol. 1972 Sep 1;21(17):2323-34. doi: 10.1016/0006-2952(72)90383-8.

Sudoxicam and related N-heterocyclic carboxamides of 4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide. Potent nonsteroidal antiinflammatory agents.舒多昔康及相关的4-羟基-2H-1,2-苯并噻嗪1,1-二氧化物的N-杂环羧酰胺。强效非甾体抗炎药。

J Med Chem. 1972 Aug;15(8):848-9. doi: 10.1021/jm00278a016.

Potent anti-inflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-dioxide.

J Med Chem. 1973 May;16(5):493-6. doi: 10.1021/jm00263a017.

Inhibition of platelet aggregation and of experimental thrombosis by sudoxicam.舒多昔康对血小板聚集及实验性血栓形成的抑制作用。

J Pharmacol Exp Ther. 1973 Dec;187(3):653-65.

Excretion and metabolism of a nonsteroidal antiinflammatory agent, 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxanilide 1,1-dioxide, in rat, dog, monkey, and man.

J Med Chem. 1971 Dec;14(12):1175-7. doi: 10.1021/jm00294a009.

Metabolism of sudoxicam by the rat, dog, and monkey.

Drug Metab Dispos. 1977 Jan-Feb;5(1):75-81.

Synthesis and antiinflammatory activity of some 3-carboxamides of 2-alkyl-4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide.

J Med Chem. 1971 Dec;14(12):1171-5. doi: 10.1021/jm00294a008.

Phenothiazine-1-carboxylic acids.

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Anti-edema and analgesic properties of delta9-tetrahydrocannabinol (THC).δ9-四氢大麻酚（THC）的抗水肿和镇痛特性。

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Green Synthetic Strategies and Pharmaceutical Applications of Thiazine and its Derivatives: An Updated Review.噻嗪及其衍生物的绿色合成策略及药物应用：最新综述。

Curr Pharm Biotechnol. 2024;25(9):1142-1166. doi: 10.2174/1389201025666230908141543.

Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam.美洛昔康的甲基决定了其对噻唑生物活化的酶特异性，与舒多昔康相比。

Toxicol Lett. 2021 Mar 1;338:10-20. doi: 10.1016/j.toxlet.2020.11.015. Epub 2020 Nov 27.

Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam.双重机制抑制美洛昔康相对于舒多昔康的生物活化作用。

Toxicology. 2020 Jul;440:152478. doi: 10.1016/j.tox.2020.152478. Epub 2020 May 11.

Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents.昔康类非甾体抗炎药的药代动力学

Clin Pharmacokinet. 1994 Feb;26(2):107-20. doi: 10.2165/00003088-199426020-00004.

Investigation of 1,3,4,9-Tetrahydro-1-popylpyrano [3,4-b] indole-1-acetic acid (prodolic acid), a new non-steroidal anti-inflammatory agent, in rats.新型非甾体抗炎药1,3,4,9-四氢-1-丙基吡喃并[3,4-b]吲哚-1-乙酸（普罗多酸）在大鼠体内的研究。

Agents Actions. 1974 Dec;4(5):370-6. doi: 10.1007/BF01964939.

The anti=inflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide).异恶丙嗪（4-羟基-2-甲基-N-（5-甲基-3-异恶唑基-2H-1,2-苯并噻嗪-3-甲酰胺1,1-二氧化物）的抗炎特性。（注：原文中“anti=inflammatory”拼写有误，正确应为“anti-inflammatory”）

Agents Actions. 1975 Aug;5(3):256-63. doi: 10.1007/BF02026440.

The effect of indomethacin on tooth extraction wound healing in rats.

Experientia. 1975 Sep 15;31(9):1056-8. doi: 10.1007/BF02326957.

Anti-inflammatory drugs and renal papillary necrosis.

Agents Actions. 1975 Oct;5(4):322-5. doi: 10.1007/BF02205239.

The effect of piroxicam on platelet aggregation.吡罗昔康对血小板聚集的作用。

Experientia. 1979 Jun 15;35(6):797-8. doi: 10.1007/BF01968256.

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