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Mutagenicity of primary and secondary carcinogens altered by normal and induced hepatic microsomes.

作者信息

Popper H, Czygan P, Greim H, Schaffner F, Garro A J

出版信息

Proc Soc Exp Biol Med. 1973 Feb;142(2):727-9. doi: 10.3181/00379727-142-37103.

DOI:10.3181/00379727-142-37103
PMID:4631999
Abstract
摘要

相似文献

1
Mutagenicity of primary and secondary carcinogens altered by normal and induced hepatic microsomes.
Proc Soc Exp Biol Med. 1973 Feb;142(2):727-9. doi: 10.3181/00379727-142-37103.
2
The effect of dietary protein deficiency on the ability of isolated hepatic microsomes to alter the mutagenicity of a primary and a secondary carcinogen.
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Cytochrome P-450 content and the ability of liver microsomes from patients undergoing abdominal surgery to alter the mutagenicity of a primary and secondary carcinogen.腹部手术患者肝脏微粒体的细胞色素P-450含量及改变一级和二级致癌物致突变性的能力。
J Natl Cancer Inst. 1973 Dec;51(6):1761-4. doi: 10.1093/jnci/51.6.1761.
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Metabolic activation of emodin in the reconstituted cytochrome P-450 system of the hepatic microsomes of rats.大黄素在大鼠肝微粒体重组细胞色素P-450系统中的代谢活化作用。
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8
The effects of pretreatment with cytochrome P-450 inducers and preincubation with a cytochrome P-450 effector on the mutagenicity of genotoxic carcinogens mediated by hepatic and renal S9 from two species of marine fish.细胞色素P-450诱导剂预处理以及与细胞色素P-450效应物预孵育对两种海鱼肝脏和肾脏S9介导的遗传毒性致癌物致突变性的影响。
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Mutagenic activation of carcinogenic N-nitrosopropylamines by rat liver: evidence for a cytochrome P-450 dependent reaction.大鼠肝脏对致癌性N-亚硝基丙胺的诱变激活作用：细胞色素P-450依赖性反应的证据。
Carcinogenesis. 1985 Mar;6(3):415-20. doi: 10.1093/carcin/6.3.415.
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Mutagenicity and rat-liver S9 demethylation kinetics of N-nitrosomethylaniline and its ring-substituted derivatives.N-亚硝基甲基苯胺及其环取代衍生物的致突变性和大鼠肝脏S9去甲基化动力学
Mutat Res. 1981 Aug;89(4):255-67. doi: 10.1016/0165-1218(81)90107-5.

引用本文的文献

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History of toxicology at the Technical University of Munich (TUM).慕尼黑工业大学（TUM）毒理学历史。
Naunyn Schmiedebergs Arch Pharmacol. 2024 Dec;397(12):9597-9602. doi: 10.1007/s00210-024-03315-0. Epub 2024 Jul 24.
2
Mutagenicity and chromosomal aberrations as an analytical tool for in vitro detection of mammalian enzyme-mediated formation of reactive metabolites.致突变性和染色体畸变作为体外检测哺乳动物酶介导的活性代谢物形成的分析工具。
Arch Toxicol. 1977 Dec 30;39(1-2):159-69. doi: 10.1007/BF00343283.
3
Repressible and inducible enzymic forms of dimethylnitrosamine-demethylase.
二甲基亚硝胺脱甲基酶的可阻遏型和诱导型酶形式。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1977 Jun 27;89(2):181-99. doi: 10.1007/BF00308517.