鸡胚培养流感疫苗的免疫原性：用宿主抗原免疫受者的抑制作用。
Immunogenicity of egg-grown influenza vaccine: inhibition by immunization of recipients with host antigen.
作者信息
Lindenmann J
出版信息
Infect Immun. 1972 Jun;5(6):883-9. doi: 10.1128/iai.5.6.883-889.1972.
Abstract
Rabbit antibody directed against normal allantoic fluid reduced the protective power of influenza vaccine prepared from egg-grown PR8 virus. A similar vaccine prepared from mouse lung virus was not inhibited. Preimmunization of mice with normal allantoic fluid or with egg-grown influenza B/Lee vaccine (crude or purified) inhibited the protective power of PR8 egg vaccine but did not affect a similar lung vaccine.
摘要
针对正常尿囊液的兔抗体降低了由鸡胚培养的PR8病毒制备的流感疫苗的保护效力。由鼠肺病毒制备的类似疫苗则未受抑制。用正常尿囊液或鸡胚培养的乙型流感病毒李株疫苗（粗制或纯化的）对小鼠进行预免疫，会抑制PR8鸡胚疫苗的保护效力，但不影响类似的肺疫苗。
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