变形链球菌致龋菌株对蔗糖葡萄糖基部分的优先利用。
Preferential utilization of the glucosyl moiety of sucrose by a cariogenic strain of Streptococcus mutans.
作者信息
Schachtele C F, Loken A E, Knudson D J
出版信息
Infect Immun. 1972 Apr;5(4):531-6. doi: 10.1128/iai.5.4.531-536.1972.
Abstract
The utilization of sucrose by a cariogenic strain of Streptococcus mutans was studied. The soluble and cell-bound sucrose-dependent, polymer-forming sucrase activities constitutively produced by the bacteria during growth on glucose were measured. About eight times more dextransucrase activity was present than levan-sucrase activity. During various states of growth on sucrose, S. mutans accumulated two to five times more insoluble and water-soluble dextran than levan. Although more of the fructosyl moiety of sucrose was therefore available to the cells, the glucosyl portion of the disaccharide was preferentially incorporated into cellular macromolecules. Glucose was shown to inhibit the utilization of fructose by S. mutans.
摘要
对变形链球菌致龋菌株利用蔗糖的情况进行了研究。测定了细菌在葡萄糖上生长期间组成性产生的可溶性和细胞结合的蔗糖依赖性聚合物形成蔗糖酶活性。葡聚糖蔗糖酶活性比果聚糖蔗糖酶活性高约八倍。在蔗糖上生长的不同阶段，变形链球菌积累的不溶性和水溶性葡聚糖比果聚糖多两到五倍。因此，虽然细胞可利用的蔗糖果糖部分更多，但二糖的葡萄糖部分优先掺入细胞大分子中。已表明葡萄糖会抑制变形链球菌对果糖的利用。
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