嗜热嗜酸芽孢杆菌中莽草酸形成β-环己基脂肪酸。一条新的生物合成途径。
The formation of -cyclohexyl-fatty acids from shikimate in an acidophilic thermophilic bacillus. A new biosynthetic pathway.
作者信息
De Rosa M, Gambacorta A, Minale L, Bu'lock J D
出版信息
Biochem J. 1972 Jul;128(4):751-4. doi: 10.1042/bj1280751.
Abstract
Labelled acetate, phenylalanine and shikimic acid were fed to Bacillus acidocaldarius. A high proportion of the (14)C incorporated from acetate and shikimate was recovered in methyl esters from the cell lipids, but such recovery of (14)C from phenylalanine was low. Only the (14)C from shikimate was selectively incorporated into 11-cyclohexylundecanoate and 13-cyclohexyltridecanoate. Degradation of these cyclohexyl-fatty acids showed that shikimate was incorporated as an intact C(7) unit.
摘要
将标记的乙酸盐、苯丙氨酸和莽草酸喂给嗜酸热硫化叶菌。从乙酸盐和莽草酸盐中掺入的（14）C有很大一部分在细胞脂质的甲酯中回收，但从苯丙氨酸中回收的（14）C则很少。只有来自莽草酸盐的（14）C被选择性地掺入11 - 环己基十一烷酸酯和13 - 环己基十三烷酸酯中。这些环己基脂肪酸的降解表明，莽草酸是以完整的C（7）单元掺入的。
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