Kappy K A, Cetrulo C L, Knuppel R A, Ingardia C J, Sbarra A J, Scerbo J C, Mitchell G W
Am J Obstet Gynecol. 1979 Jul 15;134(6):655-61. doi: 10.1016/0002-9378(79)90647-1.
A conservative approach was followed in 188 patients with premature rupture of the membranes (PROM) over a 2 year period. There were no neonatal deaths from sepsis, and only one infant showed a positive central bacteriologic culture. Fifty-seven percent of all patients less than 37 weeks' gestation had a latent period of 24 hours and 19% went beyond 7 days before labor began. Patients less than 34 weeks' gestation who received antepartum steroids for lung maturation showed no increased infectious morbidity or mortality. A conservative approach to patients with PROM seems reasonable when either prematurity and/or a cervix unfavorable for induction further complicates the pregnancy.
在两年时间里,对188例胎膜早破(PROM)患者采用了保守治疗方法。没有新生儿因败血症死亡,只有一名婴儿的中央细菌学培养呈阳性。所有孕周小于37周的患者中,57%的潜伏期为24小时,19%的患者在分娩开始前超过7天。接受产前类固醇治疗以促进肺成熟的孕周小于34周的患者,其感染发病率和死亡率并未增加。当早产和/或宫颈不利于引产使妊娠进一步复杂化时,对胎膜早破患者采取保守治疗方法似乎是合理的。