Oduro K A, Searle J F
Br Med J. 1972 Dec 9;4(5840):596-8. doi: 10.1136/bmj.4.5840.596.
505 patients with various haemoglobinopathies were given a general anaesthetic between January 1970 and February 1972. One patient with haemoglobin SC disease and one patient with sickle-cell trait (HbAS) died postoperatively. Four other patients who were sickling positive, but whose genotypes were unknown, died, one from sickle-cell crisis precipitated by haemorrhage.A simple anaesthetic technique together with good postoperative care can provide safe general anaesthesia for patients with sickle-cell states. A plea is made for simplicity in the anaesthetic management of these patients.
1970年1月至1972年2月期间,对505例患有各种血红蛋白病的患者实施了全身麻醉。1例血红蛋白SC病患者和1例镰状细胞性状(HbAS)患者术后死亡。另外4例镰状细胞试验呈阳性但基因型未知的患者死亡,其中1例死于出血引发的镰状细胞危象。一种简单的麻醉技术加上良好的术后护理可为镰状细胞状态的患者提供安全的全身麻醉。本文呼吁对这些患者的麻醉管理应简化。