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静脉注射阿莫西林在儿科患者中的药代动力学

Pharmacokinetics of intravenous amoxicillin in pediatric patients.

作者信息

Rudoy R C, Goto N, Pettit D, Uemura H

出版信息

Antimicrob Agents Chemother. 1979 Apr;15(4):628-9. doi: 10.1128/AAC.15.4.628.

Abstract

Pharmacokinetic parameters were obtained from 14 infants and children receiving intravenous amoxicillin. Peak serum values increased proportionally to the increase in dose; the serum half-life was similar in the three dose groups studied.

摘要

从14名接受静脉注射阿莫西林的婴幼儿和儿童身上获取了药代动力学参数。血清峰值与剂量增加成比例增加;在所研究的三个剂量组中,血清半衰期相似。

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本文引用的文献

1
Microbioassay of antimicrobial agents.抗菌剂的微生物测定法。
Appl Microbiol. 1970 Apr;19(4):573-9. doi: 10.1128/am.19.4.573-579.1970.
2
Pharmacokinetics of amoxicillin.
Clin Pharmacol Ther. 1974 Dec;16(6):1045-51. doi: 10.1002/cpt19741661045.
3
Amoxycillin: a new semi-synthetic penicillin.阿莫西林:一种新型半合成青霉素。
Br Med J. 1972 Jul 1;3(5817):13-6. doi: 10.1136/bmj.3.5817.13.
4
Amoxicillin, a new penicillin antibiotic.阿莫西林,一种新型青霉素类抗生素。
Antimicrob Agents Chemother. 1973 Feb;3(2):262-5. doi: 10.1128/AAC.3.2.262.

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