用β-巯基乙醇处理相思子毒素和蓖麻毒素，对它们在小鼠体内的毒性以及在无细胞系统中抑制蛋白质合成的能力产生相反的影响。 - Suppr

Suppr

超能文献

Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system.

作者信息

Olsnes S, Pihl A

出版信息

FEBS Lett. 1972 Nov 15;28(1):48-50. doi: 10.1016/0014-5793(72)80674-4.

DOI:10.1016/0014-5793(72)80674-4

PMID:4646874

Abstract

摘要

相似文献

Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system.用β-巯基乙醇处理相思子毒素和蓖麻毒素，对它们在小鼠体内的毒性以及在无细胞系统中抑制蛋白质合成的能力产生相反的影响。

FEBS Lett. 1972 Nov 15;28(1):48-50. doi: 10.1016/0014-5793(72)80674-4.

Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis.蓖麻毒素是一种抑制蛋白质合成的毒性蛋白，其两条组成肽链具有不同的生物学特性。

Biochemistry. 1973 Jul 31;12(16):3121-6. doi: 10.1021/bi00740a028.

On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells.关于毒性蛋白相思子毒素和蓖麻毒素。它们与艾氏腹水癌细胞结合及进入细胞的研究。

J Biol Chem. 1974 Jun 10;249(11):3557-62.

Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains.有毒凝集素相思子毒素和蓖麻毒素对核糖体的失活作用。毒素A链酶活性的动力学研究。

Eur J Biochem. 1975 Dec 1;60(1):281-8. doi: 10.1111/j.1432-1033.1975.tb21001.x.

Reciprocal interactions of ricin from Ricinus communis L. seeds with eukaryote ribosomes.蓖麻（Ricinus communis L.）种子中的蓖麻毒素与真核生物核糖体的相互作用。

FEBS Lett. 1977 Apr 15;76(2):166-72. doi: 10.1016/0014-5793(77)80144-0.

Molecular pharmacology of plant lectins: studies on ricin and concanavalin A (NSC-143504).植物凝集素的分子药理学：蓖麻毒素和伴刀豆球蛋白A（NSC-143504）的研究

Cancer Chemother Rep. 1974 Jul-Aug;58(4):491-501.

On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit.关于相思子毒素和蓖麻毒素抑制蛋白质合成的机制。对60-S核糖体亚基上GTP水解位点的抑制作用。

Eur J Biochem. 1975 Nov 15;59(2):573-80. doi: 10.1111/j.1432-1033.1975.tb02484.x.

Mechanism of action of the toxic lectins abrin and ricin.毒性凝集素相思子毒素和蓖麻毒素的作用机制。

Nature. 1974 Jun 14;249(458):627-31. doi: 10.1038/249627a0.

Polyribosome disaggregation in rat liver following administration of the phytotoxic proteins, abrin and ricin.给予植物毒性蛋白相思子毒素和蓖麻毒素后大鼠肝脏中的多核糖体解聚

Cancer Res. 1972 May;32(5):943-7.

NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,铜绿假单胞菌毒素对蛋白质合成的NAD依赖性抑制作用

Proc Natl Acad Sci U S A. 1975 Jun;72(6):2284-8. doi: 10.1073/pnas.72.6.2284.

引用本文的文献

Detection of Abrin Holotoxin Using Novel Monoclonal Antibodies.利用新型单克隆抗体检测相思豆毒素全毒素。

Toxins (Basel). 2017 Nov 28;9(12):386. doi: 10.3390/toxins9120386.

Effect of protein on proliferation, apoptosis and the AKT signal transduction pathway in the human endometrial carcinoma Ishikawa H cell line .蛋白质对人子宫内膜癌Ishikawa H细胞系增殖、凋亡及AKT信号转导通路的影响

Oncol Lett. 2017 May;13(5):3032-3038. doi: 10.3892/ol.2017.5830. Epub 2017 Mar 8.

Inactivation of eucaryotic ribosomes by the toxic plant proteins abrin and ricin.真核核糖体被毒蕈蛋白蓖麻毒素和相思豆毒素失活。

Mol Biol Rep. 1973 Jun;1(1):15-20. doi: 10.1007/BF00357400.

Targeting ricin to the ribosome.将蓖麻毒素靶向核糖体。

Toxicon. 2013 Jul;69:143-51. doi: 10.1016/j.toxicon.2013.02.001. Epub 2013 Feb 20.

The interactions of human neutrophils with shiga toxins and related plant toxins: danger or safety?人类中性粒细胞与志贺毒素及相关植物毒素的相互作用：危险还是安全？

Toxins (Basel). 2012 Mar;4(3):157-90. doi: 10.3390/toxins4030157. Epub 2012 Mar 1.

A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes.针对蓖麻毒素A链与核糖体的静电相互作用提出了一种两步结合模型。

Biochemistry. 2009 May 12;48(18):3853-63. doi: 10.1021/bi802371h.

Inhibition of protein synthesis by a toxic lectin from Viscum album L. (mistletoe).来自欧洲槲寄生（Viscum album L.）的一种有毒凝集素对蛋白质合成的抑制作用。

Biochem J. 1980 Sep 15;190(3):843-5. doi: 10.1042/bj1900843.

Action on ricin and its polypeptide chains on cultured hepatoma cells.蓖麻毒素及其多肽链对培养的肝癌细胞的作用。

Arch Toxicol. 1980 Mar;44(1-3):175-9. doi: 10.1007/BF00303194.

Purification and partial characterization of another form of the antiviral protein from the seeds of Phytolacca americana L. (pokeweed).从美洲商陆（垂序商陆）种子中分离纯化另一种抗病毒蛋白及其部分特性研究

Biochem J. 1982 Apr 1;203(1):55-9. doi: 10.1042/bj2030055.

Inhibition by ricin of protein synthesis in vitro. Ribosomes as the target of the toxin.蓖麻毒素对体外蛋白质合成的抑制作用。核糖体作为毒素的作用靶点。

Biochem J. 1973 Nov;136(3):677-83. doi: 10.1042/bj1360677.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验