Sommer A, Pollack I, Maumenee A E
Arch Ophthalmol. 1979 Aug;97(8):1449-54. doi: 10.1001/archopht.1979.01020020111003.
Stereoscopic fundus photographs of 17 abnormal eyes, taken in known temporal relationship to the onset of glaucomatous visual field loss, and 206 eyes of age- and race-matched controls were examined in randomized masked fashion. Width of the narrowest remaining disc rim, size of the vertical and horizontal physical cups, contour of the temporal and nasal slopes (vertical ovalness), and a newly described parameter, thickness of the nerve fiber layer as it crosses the disc rim, were all useful for distinguishing patients with impending or established visual field loss. None, however, was as effective as defects in the nerve fiber layer, the only parameter displaying sufficient promise as a clinical screening tool to warrant initiation of large-scale prospective evaluation.
对17只异常眼睛的立体眼底照片进行了随机盲法检查,这些照片是在已知与青光眼性视野缺损发作的时间关系下拍摄的,同时还检查了206只年龄和种族匹配的对照眼睛。剩余最窄视盘边缘的宽度、垂直和水平生理性杯盘的大小、颞侧和鼻侧斜坡的轮廓(垂直椭圆形)以及一个新描述的参数——神经纤维层穿过视盘边缘处的厚度,所有这些对于区分即将发生或已发生视野缺损的患者都很有用。然而,没有一个参数像神经纤维层缺损那样有效,神经纤维层缺损是唯一有足够前景作为临床筛查工具从而值得启动大规模前瞻性评估的参数。