Holland C, Heaton K W
Br Med J. 1972 Sep 16;3(5828):672-5. doi: 10.1136/bmj.3.5828.672.
In the Bristol clinical area the frequency of gall bladder operations rose by a factor of 3.4 between 1940 and 1970, the greatest increase occurring in the 1950s. The increase took place in all age groups, but was greatest in the under-30s and in men. Numerous factors affect the chance of a patient with gall stones being operated on, but a change of this magnitude suggests there has been a substantial rise in the incidence of gall stones since the second world war. This belief is supported by data from the nationwide Hospital In-patient Enquiry.
在布里斯托尔临床地区,1940年至1970年间胆囊手术的频率增长了3.4倍,最大增幅出现在20世纪50年代。各年龄组均有增长,但30岁以下人群和男性的增幅最大。许多因素会影响胆结石患者接受手术的几率,但如此大幅度的变化表明,自第二次世界大战以来胆结石的发病率大幅上升。这一观点得到了全国医院住院病人调查数据的支持。