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[分娩时窒息后脑的形态学变化(智力发育迟缓的发病机制)]

[Morphologic changes in the brain after sustaining asphyxia during labor (pathogenesis of mental retardation)].

作者信息

Kazakova P B, Khokhrina N T

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(7):857-64.

PMID:465152
Abstract

An analysis was accomplished of pathomorphological changes in the brains of 10 newborns, who died of intranatal asphyxia and of 1 adult brain with mental retardation, due to asphyxia during delivery. The dynamics of hypoxic changes of an irreversible character in the brain of the newborn and the existence of chronic hypoxic encephalopathy with pronounced cellular devastation in the late period of asphyxia indicate common genesis of the pathological process in the brain, conditioning its progression. The role of intranatal asphyxia in the pathogenesis of changes in postnatal development of neuropsychic activity is discussed.

摘要

对10例死于产时窒息的新生儿及1例因分娩时窒息导致智力发育迟缓的成人的大脑进行了病理形态学变化分析。新生儿大脑中不可逆性缺氧变化的动态过程以及窒息后期存在伴有明显细胞破坏的慢性缺氧性脑病,表明大脑病理过程有共同的发生机制,这决定了其进展。文中讨论了产时窒息在神经精神活动产后发育变化发病机制中的作用。

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