Benbassat J, Penchas S, Ligumski M
Br J Haematol. 1979 Jun;42(2):207-14. doi: 10.1111/j.1365-2141.1979.tb01125.x.
The available data on 321 published cases of splenectomy in agnogenic myeloid metaplasia were reviewed. Anaemia and thrombopenia were the most common indications for this operation. Patients reported after 1940 had a median postoperative survival of 13 months. Their postoperative mortality was 7.5% after 2 d and 25.7% after 3 months. The postoperative mortality was significantly higher when the weight of the spleen exceeded 2000 g, or in patients with platelet count less than 70 X 10(9)/l. The most common causes of death were infections (34.4%), cardiac or thromboembolic events (26.4%) and haemorrhage (17.6%). Leukaemic transformation was reported in 11.2% of the cases.
对321例已发表的原发性骨髓化生脾切除术病例的现有数据进行了回顾。贫血和血小板减少是该手术最常见的指征。1940年后报告的患者术后中位生存期为13个月。术后2天的死亡率为7.5%，3个月后为25.7%。当脾脏重量超过2000g或血小板计数低于70×10⁹/L时，术后死亡率显著更高。最常见的死亡原因是感染（34.4%）、心脏或血栓栓塞事件（26.4%）和出血（17.6%）。11.2%的病例报告有白血病转化。
