原发性骨髓化生行脾切除术：可能具有预后意义的因素
Splenectomy in agnogenic myeloid metaplasia: factors of possible prognostic significance.
作者信息
Penchas S, Steinwel A, Sukenik S, Benbassat J
出版信息
Postgrad Med J. 1982 Apr;58(678):212-5. doi: 10.1136/pgmj.58.678.212.
The available data of 338 cases of splenectomy in agnogenic myeloid metaplasia published since 1940 were retrieved from the literature and analysed. Postoperative survival was significantly shorter in patients with anaemia, massive splenomegaly or elevated serum alkaline phosphatase. Younger age or normal platelet counts were associated with a longer postoperative survival than that in older patients and in patients with low platelet counts respectively. The shortest median postoperative survival was found in: patients in whom serum alkaline phosphatase exceeded twice the upper limit of the normal; patients with anaemia (less than 10 g/dl haemoglobin) and massive splenomegaly (above 3 kg); and patients with anaemia and a splenic weight less than one kg.
检索并分析了自1940年以来发表的关于338例原发性骨髓化生脾切除术的可用数据。贫血、巨脾或血清碱性磷酸酶升高的患者术后生存期明显缩短。较年轻患者或血小板计数正常的患者术后生存期分别比老年患者和血小板计数低的患者长。术后中位生存期最短的患者为：血清碱性磷酸酶超过正常上限两倍的患者；贫血（血红蛋白低于10g/dl）且巨脾（超过3kg）的患者；以及贫血且脾脏重量小于1kg的患者。
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