血液透析中血液接触激活的研究。
Studies of contact activation of blood in haemodialysis.
作者信息
Wardle E N, Piercy D A
出版信息
J Clin Pathol. 1972 Dec;25(12):1045-9. doi: 10.1136/jcp.25.12.1045.
Abstract
A study of patients on Kiil and Travenol coil dialysis has shown that kallikrein esterase, the kinin precursor, is increased in the venous blood during dialysis and that this is accompanied by an increase in the venous effluent of the dialysers. In addition Hageman factor depletion and an increase of platelet factor 4 has been found in the venous effluent. Such studies indicate surface activation of coagulation in the dialysers and will be of use in future studies of the suitability of different dialysers.
摘要
一项针对接受基尔（Kiil）和特拉韦诺尔（Travenol）盘管透析患者的研究表明，激肽原酶（激肽前体）在透析期间静脉血中含量增加，且透析器静脉流出液也随之增加。此外，已发现静脉流出液中有哈格曼因子消耗以及血小板因子4增加。此类研究表明透析器中存在凝血的表面激活现象，这将有助于未来对不同透析器适用性的研究。
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