Duguesnoy R J, Anderson A J, Tomasulo P A, Aster R H
Blood. 1979 Sep;54(3):595-9.
With data on 91 alloimmunized thrombocytopenic patients and 389 donor-recipient pairs matched or selectively mismatched for HLA antigens, it was observed that ABO incompatibility significantly reduced the effectiveness of platelet transfusions. The mean 24-hr recovery of platelets from histocompatible donors and from donors selectively mismatched for cross-reactive HLA antigens was decreased by approximately 23% if the donor typed for blood group A and/or B not found in the recipient. Thus, the reduction in platelet recovery associated with ABO incompatibility is not of a magnitude that would contraindicate transfusion of ABO-mismatched platelets.
对91例同种免疫性血小板减少症患者以及389对在HLA抗原方面匹配或选择性不匹配的供受者配对数据进行分析后发现，ABO血型不相容显著降低了血小板输注的效果。如果供者血型为受者所没有的A和/或B型，那么来自组织相容性供者以及与交叉反应性HLA抗原选择性不匹配的供者的血小板平均24小时回收率会降低约23%。因此，与ABO血型不相容相关的血小板回收率降低幅度不至于成为输注ABO血型不匹配血小板的禁忌。
