黑色素瘤患者血浆中的5-S-半胱氨酰多巴及该氨基酸的肾脏清除率。
5-S-cysteinyldopa in the plasma of melanoma patients and the renal clearance of this amino acid.
作者信息
Agrup G, Andersson T, Falck B, Persson K, Rorsman H, Rosengren A M, Rosengren E
出版信息
Acta Derm Venereol. 1975;55(1):5-6.
PMID:46673
Abstract
5-S-cysteinyldopa has been demonstrated in the plasma of two patients with metastases of malignant melanoma and a high excretion rate of 5-S-cysteinyldopa in the urine. In one patient the plasma clearance of 5-S-cysteinyl dopa was 30 ml/min and in the other 69 ml/min. These clearance values were 43 and 45%, respectively, of the creatinine clearance in the two patients.
摘要
在两名患有恶性黑色素瘤转移且尿中5-S-半胱氨酰多巴排泄率高的患者血浆中已证实存在5-S-半胱氨酰多巴。其中一名患者5-S-半胱氨酰多巴的血浆清除率为30毫升/分钟，另一名患者为69毫升/分钟。这些清除率值分别为两名患者肌酐清除率的43%和45%。
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