Frosch P J, Kligman A M
Contact Dermatitis. 1979 Mar;5(2):73-81. doi: 10.1111/j.1600-0536.1979.tb04802.x.
For assessing skin reactions to irritants and allergens, chambers which confine the test substance to the site of application are much superior to conventional patch tests. Because the concentration and volume do not change appreciably, the method allows for quantification and yields more reproducible results. A new aluminum chamber has been designed which is more useful than its predecessor, the Finn chamber, mainly because of its increased capacity. Data are given to show that the intensity of irritant and allergic reactions is dependent on the quantities applied.
对于评估皮肤对刺激物和过敏原的反应，将测试物质限制在涂抹部位的腔室比传统的斑贴试验优越得多。由于浓度和体积不会明显变化，该方法允许进行定量并产生更可重复的结果。一种新设计的铝制腔室比其前身芬兰腔室更有用，主要是因为其容量增加。给出的数据表明，刺激和过敏反应的强度取决于所应用的量。
