Buzina R, Jusić M, Milanović N, Sapunar J, Brubacher G
Int J Vitam Nutr Res. 1979;49(2):136-43.
The effect of riboflavin administration on iron metabolism was studied in a group of riboflavin-deficient children with Erythrocyte Glutathione Reductase (EC 1.6.4.2) reactivation above 1.20. The results have shown that the administration of riboflavin has resulted in a decrease of serum iron as well as in transferrin saturation which was accompanied by an increase in blood hemoglobin in subjects with initially lower hemoglobin values (less than or equal to 13.5 g/100 ml). There was, however, no change in blood hemoglobin in the group with initially higher hemoglobin values (greater than or equal to 14.0 g/100 ml). The results suggest that inadequate riboflavin intake may affect the iron utilization. The possible mechanism of riboflavin action on iron utilization is discussed.
在一组红细胞谷胱甘肽还原酶（EC 1.6.4.2）再激活率高于1.20的核黄素缺乏儿童中，研究了核黄素给药对铁代谢的影响。结果表明，核黄素给药导致血清铁减少以及转铁蛋白饱和度降低，同时，初始血红蛋白值较低（小于或等于13.5 g/100 ml）的受试者血液血红蛋白增加。然而，初始血红蛋白值较高（大于或等于14.0 g/100 ml）的组中血液血红蛋白没有变化。结果表明，核黄素摄入不足可能会影响铁的利用。本文讨论了核黄素对铁利用作用的可能机制。
