Brand U, Spiliopoulos A, Mégevand R P
Helv Chir Acta. 1979 May;46(1-2):159-62.
Until 1971 13 cases of breast cancer in men were observed in our service. In the world literature it accounts for 1% of all cancer of the breast; in our series we have found 4% of all breast cancer. Men present themselves for treatment later and with more advanced local signs than women. In our series, the greatest number of cases occurs near the seventies in men, which is about twenty years later than in women. The etiology is remained unknown, but Klinefelter's disease seems to be a risk for breast cancer. If there are no metastasis, we prefer in our service the surgical treatment as unique treatment. If possible the operation of Patey is realised, but sometimes we have to do a simple mastectomy only as a safe alternative for poor risk patient. In case of metastatic breast cancer the adjuvant treatment was X-ray therapy, chemotherapy and in some of our cases hormonotherapy. We do not have any experience with suppressive hormonal therapy such as orchiectomy or adrenalectomy. Most of the authors think that prognosis of breast cancer in males is worse than in women; the constant central localization of the tumour may be an explanation for that. The fate of women with central lesions is as poor as in males.
截至1971年，我们科室共观察到13例男性乳腺癌患者。在世界文献中，男性乳腺癌占所有乳腺癌的1%；在我们的病例系列中，其占所有乳腺癌的4%。男性患者比女性患者就诊时间更晚，局部体征也更严重。在我们的病例系列中，男性患者发病最多的年龄在70岁左右，比女性晚约20年。病因尚不清楚，但克兰费尔特综合征似乎是乳腺癌的一个风险因素。如果没有转移，我们科室倾向于将手术作为唯一的治疗方法。如果可能，会实施帕蒂手术，但有时对于高风险患者，我们只能进行单纯乳房切除术作为安全的替代方案。对于转移性乳腺癌，辅助治疗包括放疗、化疗，在我们的一些病例中还包括激素治疗。我们没有任何关于去势或肾上腺切除术等抑制性激素治疗的经验。大多数作者认为男性乳腺癌的预后比女性差；肿瘤持续位于中央部位可能是一个原因。患有中央病变的女性患者预后与男性一样差。
