Functionalization of penicillins at carbon 6 via N-acylimines. 6-Hydroxypenicillin. Substituted penicillins and cephalosporins. 8.
作者信息
Firestone R A, Christensen B G
出版信息
J Org Chem. 1973 Apr 6;38(7):1436-7. doi: 10.1021/jo00947a051.
PMID:4694237
Abstract
摘要
相似文献
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Functionalization of penicillins at carbon 6 via N-acylimines. 6-Hydroxypenicillin. Substituted penicillins and cephalosporins. 8.通过N-酰基亚胺对青霉素6位进行官能团化。6-羟基青霉素。取代青霉素和头孢菌素。8.
J Org Chem. 1973 Apr 6;38(7):1436-7. doi: 10.1021/jo00947a051.
2
Electronic structures of cephalosporins and penicillins. 4. Modeling acylation by the beta-lactam ring.头孢菌素和青霉素的电子结构。4. β-内酰胺环酰化作用的建模
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3
Chemical relationships between cephalosporins and penicillins.头孢菌素与青霉素之间的化学关系。
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4
CNDO-2 study of the antibacterial activity of penicillins and cephalosporins.
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Electronic structures of cephalosporins and penicillins. 2. Disulfide and beta-lactam chromophores. Structure-activity relationships.头孢菌素和青霉素的电子结构。2. 二硫键和β-内酰胺发色团。构效关系。
J Med Chem. 1973 Nov;16(11):1195-9. doi: 10.1021/jm00269a001.
6
Synthetic studies related to nuclear analogues of the penicillins and cephalosporins.与青霉素和头孢菌素的核类似物相关的合成研究。
J Chem Soc Perkin 1. 1973;5:479-84. doi: 10.1039/p19730000479.
7
Effect of 6-alpha substitution in penicillins and 7-beta substitution in cephalosporins upon beta-lactam reactivity.青霉素6-α位取代和头孢菌素7-β位取代对β-内酰胺反应活性的影响。
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Penicillins and cephalosporins.青霉素和头孢菌素。
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9
Substituent effects upon the base hydrolysis of penicillins and cephalosporins. Competitive intramolecular nucleophilic amino attack in cephalosporins.
J Med Chem. 1974 May;17(5):523-7. doi: 10.1021/jm00251a011.
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Chemical transformations of penicillins and cephalosporins. Mechanism and stereochemistry of the interconversions of penam and cepham systems.青霉素和头孢菌素的化学转化。青霉烷和头孢烷体系相互转化的机制和立体化学。
J Am Chem Soc. 1975 May 28;97(11):3192-8. doi: 10.1021/ja00844a045.
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Kinetics and stereochemistry of hydrolysis of an N-(phenylacetyl)-α-hydroxyglycine ester catalyzed by serine β-lactamases and DD-peptidases.丝氨酸β-内酰胺酶和 DD-肽酶催化的 N-(苯乙酰基)-α-羟基甘氨酸酯的水解动力学和立体化学。
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