Wald N, Howard S, Smith P G, Kjeldsen K
Br Med J. 1973 Mar 31;1(5856):761-5. doi: 10.1136/bmj.1.5856.761.
In a cross-sectional study carboxyhaemoglobin (COHb) levels in tobacco smokers were found to provide a better indication of a person's risk of having developed certain atherosclerotic diseases, including ischaemic heart disease, than the smoking history. In the age group 30-69 years a person with a COHb level of 5% or more was found to be 21 times (lower 95% confidence limit 3.3 times) as likely to be affected by these diseases as another person of the same age and sex with similar smoking history and current smoking habits but with a COHb level of less than 3%.
在一项横断面研究中发现,与吸烟史相比,吸烟者的碳氧血红蛋白(COHb)水平能更好地表明一个人患某些动脉粥样硬化疾病(包括缺血性心脏病)的风险。在30 - 69岁年龄组中,发现碳氧血红蛋白水平达到或超过5%的人与年龄、性别相同,吸烟史和当前吸烟习惯相似,但碳氧血红蛋白水平低于3%的人相比,患这些疾病的可能性高21倍(95%置信下限为3.3倍)。