吸烟、一氧化碳与动脉粥样硬化疾病
Smoking, carbon monoxide, and atherosclerotic diseases.
作者信息
Heliövaara M, Karvonen M J, Vilhunen R, Punsar S
出版信息
Br Med J. 1978 Feb 4;1(6108):268-70. doi: 10.1136/bmj.1.6108.268.
Abstract
Smoking habits and random measurements of the proportion of haemoglobin bound to carbon monoxide (COHb%) were examined for their association with atherosclerotic diseases in 1068 men aged 55 to 74 years from rural areas of Finland. COHb% and smoking history were similarly associated with claudication and coronary heart disease. Random measurements of COHb% did not show a better overall relation to the prevalence of atherosclerotic diseases than smoking history, though COHb% showed a stronger association with a probable previous myocardial infarction. Further studies are needed to clarify the role of carbon monoxide in atherosclerosis.
摘要
对来自芬兰农村地区的1068名年龄在55至74岁之间的男性的吸烟习惯以及血红蛋白与一氧化碳结合比例（碳氧血红蛋白百分比，COHb%）的随机测量值进行了检查，以探究它们与动脉粥样硬化疾病之间的关联。COHb%和吸烟史与跛行和冠心病的关联相似。尽管COHb%与既往可能发生的心肌梗死的关联更强，但与吸烟史相比，COHb%的随机测量值并未显示出与动脉粥样硬化疾病患病率存在更好的总体关系。需要进一步的研究来阐明一氧化碳在动脉粥样硬化中的作用。
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