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婴儿猝死症的病理学

The pathology of cot deaths.

作者信息

Herbert A, Andrews P S

出版信息

J Pathol. 1979 May;128(1):39-48. doi: 10.1002/path.1711280107.

DOI:10.1002/path.1711280107
PMID:469651
Abstract

An examination of the pathological features of 12 consecutive cases of sudden death in infancy was undertaken with particular reference to the lung changes used a combined radiological and pathological study of formalin vapour-inflated lungs. Certain common features in the cases in which there are no post mortem changes to explain death (typical cot deaths) are described and compared with cases with an acceptable cause of death and with control cases. It was concluded that severe dehydration is a potentially avoidable factor underlying cot deaths and many other sudden infant deaths with no explainable causes; that petechial haemorrhages are a constant feature of cot deaths and indicate a respiratory/hypoxic mode of death; that absence of petechiae indicates some other explanation for death. It is suggested that the minor respiratory or other infections which are usually present at autopsy in cot deaths may sometimes exaggerate a preexisting state of dehydration and that the dehydration may contribute more directly to death than the infection.

摘要

对12例婴儿猝死的连续病例进行了病理学特征检查,特别参考了使用福尔马林蒸汽充气肺的放射学和病理学联合研究的肺部变化。描述了那些没有尸检变化来解释死亡的病例(典型的婴儿床死亡)中的某些共同特征,并与有可接受死因的病例和对照病例进行了比较。得出的结论是,严重脱水是婴儿床死亡以及许多其他无明显死因的婴儿猝死的一个潜在可避免因素;瘀点出血是婴儿床死亡的一个恒定特征,表明是呼吸/缺氧死亡方式;没有瘀点表明死亡有其他原因。有人提出,婴儿床死亡尸检时通常存在的轻微呼吸道或其他感染有时可能会加重先前存在的脱水状态,而且脱水可能比感染更直接导致死亡。

相似文献

1
The pathology of cot deaths.婴儿猝死症的病理学
J Pathol. 1979 May;128(1):39-48. doi: 10.1002/path.1711280107.
2
Pathological findings in SIDS.婴儿猝死综合征的病理检查结果
J Clin Pathol. 1992 Nov;45(11 Suppl):11-6.
3
The frequency and significance of alveolar haemosiderin-laden macrophages in sudden infant death.肺泡含铁血黄素巨噬细胞在婴儿猝死中的频率及意义
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Sudden death in infancy in Inner North London.伦敦北部内城区的婴儿猝死。
J Pathol. 1975 Sep;117(1):55-61. doi: 10.1002/path.1711170108.
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[Bacterial toxins as cause of sudden infant death (author's transl)].[细菌毒素作为婴儿猝死的原因(作者译)]
Med Klin. 1978 Jun 2;73(22):827-32.
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A comparison of respiratory symptoms and inflammation in sudden infant death syndrome and in accidental or inflicted infant death.婴儿猝死综合征与意外或受虐婴儿死亡的呼吸道症状及炎症比较
Am J Forensic Med Pathol. 2003 Mar;24(1):1-8. doi: 10.1097/01.PAF.0000051520.92087.C3.
7
Cot deaths. I. The relevance of dehydration in some cot deaths.婴儿猝死。一、脱水在某些婴儿猝死中的相关性。
Health Visit. 1975 Oct;48(10):378-9.
8
The role of post-mortem investigations in determining the cause of sudden unexpected death in infancy.尸检调查在确定婴儿猝死原因中的作用。
Arch Dis Child. 2008 Dec;93(12):1048-53. doi: 10.1136/adc.2007.136739. Epub 2008 Jun 30.
9
Sterile site infection at autopsy in sudden unexpected deaths in infancy.婴儿猝死尸检时的无菌部位感染
Arch Dis Child. 2009 Apr;94(4):303-7. doi: 10.1136/adc.2007.135939. Epub 2008 Sep 15.
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Interstitial haemosiderin in the lungs of sudden infant death syndrome: a histological hallmark of 'near-miss' episodes?婴儿猝死综合征患儿肺部的间质含铁血黄素:“濒死”发作的组织学标志?
J Pathol. 1985 Jan;145(1):53-8. doi: 10.1002/path.1711450105.

引用本文的文献

1
Cot deaths in Edinburgh: infant feeding and socioeconomic factors.爱丁堡的婴儿猝死:婴儿喂养及社会经济因素
J Epidemiol Community Health. 1980 Mar;34(1):35-41. doi: 10.1136/jech.34.1.35.