Mason J K, Harkness R A, Elton R A, Bartholomew S
J Epidemiol Community Health. 1980 Mar;34(1):35-41. doi: 10.1136/jech.34.1.35.
One hundred and twenty-six consecutive cases of sudden infant death syndrome (SIDS) in the Edinburgh area have been studied with particular reference to the interrelationship of feeding, associated biochemical changes, and social status. There was an excess of cases born to parents in Social Classes IV and V: the effect was maximal in children who dies beyond 12 weeks of age. A low-grade uraemia was discovered in approximately one-fifth of the cases; analysis showed this to be related most strongly to bottle-feeding. Feeding habits were found to be associated with social class and this accounted for the relationship between bottle-feeding and the youth of mothers and also for an apparent relationship between uraemia in the infant and social class of the mother. Mothers of SIDS children were younger than expected and SIDS was found to be electrolyte imbalance is common in SIDS cases, nor did the findings support the suggestion that cross-infection due to overcrowding is an important aetiological factor. The significant factors of young motherhood, low social status, bottle-feeding, and mild uraemia in the babies are interrelated and seem to focus attention on unwitting 'mothering problems'. It is, however, not easy to see how this, or any other hypothesis, can account for all cases of SIDS.
对爱丁堡地区连续126例婴儿猝死综合征(SIDS)病例进行了研究,特别关注喂养方式、相关生化变化及社会地位之间的相互关系。社会阶层为IV和V的父母所生的病例过多:这种影响在12周龄后死亡的儿童中最为明显。约五分之一的病例发现有轻度尿毒症;分析表明,这与奶瓶喂养关系最为密切。发现喂养习惯与社会阶层有关,这解释了奶瓶喂养与母亲年轻之间的关系,也解释了婴儿尿毒症与母亲社会阶层之间的明显关系。SIDS患儿的母亲比预期的年轻,且发现SIDS病例中常见电解质失衡,研究结果也不支持因过度拥挤导致交叉感染是一个重要病因的观点。年轻母亲、低社会地位、奶瓶喂养和婴儿轻度尿毒症这些重要因素相互关联,似乎都将注意力集中在不经意间出现的“育儿问题”上。然而,很难看出这一假设或任何其他假设如何能解释所有SIDS病例。