β地中海贫血：淋巴细胞培养中染色体异常增加。
Beta-thalassaemia: increased chromosomal anomalies in lymphocyte cultures.
作者信息
Côté G B, Papadakou-Lagoyanni S
出版信息
J Med Genet. 1979 Feb;16(1):52-5. doi: 10.1136/jmg.16.1.52.
Abstract
Lymphocyte cultures from homozygotes for the beta-thalassaemia gene were found to contain chromosomal gaps, breaks, and rearrangements more often than those from controls. Culture time seemed to have a determinant effect on the results. The possible influence of folic acid deficiency is discussed.
摘要
研究发现，β地中海贫血基因纯合子的淋巴细胞培养物中出现染色体间隙、断裂和重排的情况比对照组更为常见。培养时间似乎对结果有决定性影响。文中还讨论了叶酸缺乏可能产生的影响。
Zotero 插件